Endocrine Abstracts

Leptin is a hormone produced mainly from adipose tissue, which plays a major role in energy homeostasis. Its receptor Ob-R exists in five splice variants (Ob-Ra, b, c, d and e) with differing signal transduction abilities. The function of leptin and its receptor in development is not yet fully understood. This study determined the expression of leptin and its receptor in a number of fetal endocrine tissues.Tissue samples were obtained from 7 fetal sheep ...